GLP-1 Medications for Weight Loss: What to Expect in the First 90 Days
GLP-1 receptor agonists — including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) — have reshaped the conversation around medical weight management. For many patients, these medications produce meaningful weight loss that diet and exercise alone couldn't achieve. But starting GLP-1 therapy comes with a learning curve, and understanding what to expect during the first 90 days helps patients stay the course and optimize their results.Weeks 1–4: The Adjustment PhaseMost GLP-1 medications are initiated at a low dose and titrated upward over weeks or months to minimize gastrointestinal side effects. During the first few weeks, patients commonly experience nausea, reduced appetite,...
